Assessing Long-term Outcomes of Germ Cell Tumors Diagnosed in Childhood, Adolescent and Young Adults Using Administrative Data

Germ cell tumors (GCTs) are rare cancers that begin in cells that form eggs or sperm. They usually occur in the ovaries, testes, or along the body’s midline. Thanks to effective treatments like surgery and chemotherapy, most people diagnosed with GCT, especially children, teens, and young adults, now survive their cancer. However, some survivors may develop long-term health problems such as heart disease, high blood pressure, or mental health challenges years after treatment.

This study will look at individuals in British Columbia who were diagnosed with GCT between 1990 and 2020 at ages 0-39 years. By comparing survivors to people without cancer, researchers aim to understand how cancer treatments may affect long-term heart and mental health. The findings will help improve follow-up care and support for survivors of this highly curable cancer.